Risks Involved
Extraction of cells from the embryo can cause damage to the embryo and prevent it from developing after transferring. Also since a few cells need not represent the embryo, a healthy embryo may give a negative test result. There is the added risk that all of the embryos are found to have abnormal chrmomosomes, so there are no embryos available for transfer.
What is PGT?
PGT stands for Preimplantation Genetic Testing. It is a scientific technique used during an IVF cycle to examine the genetic makeup of embryos before they are transferred to the uterus. A small number of cells are carefully biopsied from each embryo and sent for genetic analysis. The goal is to identify embryos that are chromosomally normal or free from a specific inherited condition — increasing the likelihood of a successful pregnancy and reducing the risk of miscarriage or passing on a genetic disorder. PGT is not a standalone procedure; it is always performed as part of an IVF cycle. For couples who have experienced repeated IVF failure, recurrent miscarriage, or carry a known genetic condition, PGT can be a genuinely meaningful step forward. The best fertility hospitals in Bangalore offer PGT as part of a comprehensive IVF programme with in-house genetic expertise.
What is preimplantation genetic diagnosis?
Preimplantation Genetic Diagnosis — now more commonly referred to as PGT-M (Preimplantation Genetic Testing for Monogenic disorders) — is a specific type of genetic testing performed on embryos to detect a known single-gene disorder before implantation. It was developed for couples who carry or are affected by serious inherited conditions such as sickle cell anaemia, thalassemia, cystic fibrosis, Huntington’s disease, or BRCA mutations. By testing embryos before transfer, couples can select only those that are unaffected by the condition in question — significantly reducing the risk of passing it on to their child. PGD/PGT-M requires detailed genetic preparation before the IVF cycle begins, including carrier testing and the development of a custom genetic probe specific to the family’s mutation. At Aspire Fertility Center Bangalore, couples considering PGT-M receive a thorough pre-treatment genetic counselling session to understand the process, its possibilities, and its limitations before making any decisions.
What factors should I consider when selecting a facility for PGT-M?
Choosing the right facility for PGT-M is one of the most important decisions in your fertility journey. Here are the key factors to evaluate:
• Genetic expertise on-site or through a trusted partner lab — PGT-M requires a custom genetic probe built specifically for your mutation. Not all clinics have this capability; confirm whether the centre works with an accredited genetics laboratory.
• IVF success rates with PGT — Ask specifically about outcomes for couples who have undergone PGT-M, not just overall IVF statistics.
• Genetic counselling availability — A dedicated genetic counsellor should be part of your care team, helping you interpret results and make informed decisions.
• Embryology lab quality — The biopsy step requires a highly skilled embryologist. A poorly performed biopsy can damage the embryo or yield inconclusive results.
• Transparent communication — The facility should be clear about what PGT-M can and cannot detect, success probabilities, and what happens if no suitable embryos are found.
• Experience with your specific condition — Some centres have more experience with certain mutations than others. It is worth asking directly.
The best fertility hospitals in Bangalore will offer all of the above as standard — and will never rush you into a decision before you feel fully informed.
Can I get a consultation via telemedicine for PGT treatment?
Yes — an initial telemedicine consultation for PGT is entirely possible and increasingly common, particularly for couples who live outside Bangalore or prefer to have a preliminary conversation from the comfort of their home before committing to an in-person visit. During a teleconsultation, a fertility specialist can review your medical history, previous IVF records, genetic test results, and family history to give you an initial assessment of whether PGT is appropriate for your situation. That said, the actual IVF and PGT cycle — including monitoring scans, egg retrieval, embryo biopsy, and transfer — will require in-person visits to the clinic. Aspire Fertility Center Bangalore offers teleconsultation appointments for couples who want to understand their options before taking the next step. You can reach us at 080-42121313 or email info@aspirefertility.in to schedule your consultation.
How do I schedule an initial consultation for reproductive genetic services?
Scheduling an initial consultation for reproductive genetic services is straightforward. Start by identifying a fertility centre that offers both IVF and genetic testing under one roof — this ensures your care is coordinated rather than fragmented across multiple providers. When you contact the centre, let them know you are specifically interested in PGT or genetic counselling so they can match you with the right specialist from the outset. Bring any relevant documents to your first appointment — previous semen analyses, hormone test results, prior IVF records, or genetic reports if you or your partner have already been tested. The best fertility hospitals in Bangalore typically offer dedicated genetic counselling as part of their fertility assessment process, meaning you do not need a separate referral to access this service. At Aspire Fertility Center Bangalore, you can book an appointment by calling 080-42121313, reaching us on 9620004610 or 9620006410, or emailing info@aspirefertility.in.
Are there any top-rated fertility centres specialising in PGT treatment?
Yes — several fertility centres across India offer PGT as part of their IVF services, but the quality of genetic testing, embryology expertise, and counselling support varies significantly between clinics. When looking for a top-rated centre for PGT in Bangalore, prioritise those with a strong IVF track record, an in-house or accredited partner embryology and genetics lab, and a team experienced in handling complex cases involving chromosomal or monogenic conditions. Aspire Fertility Center Bangalore is recognised as one of the leading centres for advanced fertility treatment in the city, offering PGT as part of a personalised IVF programme designed around each couple’s specific genetic and reproductive needs. With centres in HSR Layout and Sarjapur-Marathahalli Road, specialist care is accessible across Bangalore.
What are the costs involved in PGT treatment at reputed centres?
The cost of PGT treatment in India varies depending on the type of testing required and the centre where it is performed. As a general guide:
• PGT-A (chromosomal screening): typically ranges from ₹40,000 to ₹80,000 per cycle, in addition to the base IVF cost.
• PGT-M (single-gene disorder testing): generally higher — ranging from ₹80,000 to ₹1,50,000 or more — due to the need for a custom genetic probe.
• PGT-SR (structural rearrangements): pricing is similar to PGT-M and depends on the complexity of the chromosomal change involved.
These figures cover the biopsy and laboratory analysis; the overall IVF cycle cost is separate. The best fertility hospitals in Bangalore will provide a clear, itemised cost breakdown before your cycle begins — so there are no surprises along the way. Always ask for a written quote that specifies what is and is not included, and whether repeat testing is charged separately if inconclusive results are returned.
What are the steps involved in PGT-A during an IVF cycle?
PGT-A (Preimplantation Genetic Testing for Aneuploidies) is used to screen embryos for abnormal chromosome numbers before transfer. Here is how it fits into an IVF cycle:
• Ovarian stimulation — The woman takes hormone injections to stimulate the ovaries to produce multiple eggs.
• Egg retrieval — Mature eggs are collected under mild sedation in a short procedure.
• Fertilisation — Eggs are fertilised with sperm in the laboratory using IVF or ICSI.
• Embryo culture — Fertilised embryos are grown in the lab for 5 to 6 days until they reach the blastocyst stage.
• Embryo biopsy — A skilled embryologist removes a small number of cells (typically 5 to 8) from the outer layer of each blastocyst. This does not harm the embryo.
• Genetic analysis — The biopsied cells are sent to a genetics laboratory for chromosomal analysis, which takes approximately 1 to 2 weeks.
• Embryo freezing — All biopsied embryos are frozen while awaiting results.
• Frozen embryo transfer — Once results are available, chromosomally normal embryos are selected for transfer in a subsequent cycle.
Clinics that are among the best fertility hospitals in Bangalore perform each of these steps with precision — particularly the biopsy, which requires advanced embryological skill to ensure embryo integrity is preserved throughout.
Which clinics in India offer advanced PGT treatment services?
Advanced PGT treatment is available at select fertility centres across major Indian cities including Bangalore, Mumbai, Delhi, Chennai, and Hyderabad. When assessing clinics for PGT, the most important indicators of quality are: accreditation of the genetics laboratory, the embryology team’s biopsy experience, the range of PGT types offered (PGT-A, PGT-M, and PGT-SR), access to genetic counselling, and transparency around success rates and costs. In Bangalore specifically, Aspire Fertility Center stands out as a trusted destination for advanced fertility and genetic treatment — with a specialist team, two clinic locations for accessibility, and a patient-first approach that covers everything from your first consultation to your embryo transfer.
